Combined Thrombophilia in a Young Male Presenting as Life Threatening Pulmonary Embolism
Published: September 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/27336.10582
Akshyaya Pradhan, Ayush Shukla, Mili Jain, Anupam Mehrotra, Rishi Sethi
1. Assistant Professor, Department of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
2. Senior Resident, Department of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
3. Assistant Professor, Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.
4. Assistant Professor, Department of Cardiology, Ganesh Shankar Vidyarthi Memorial College, Kanpur, Uttar Pradesh, India.
5. Professor, Department of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Correspondence
Dr. Ayush Shukla,
Senior Resident, Department of Cardiology, King Georges Medical University, Lucknow-226003, Uttar Pradesh, India.
E-mail: ayushgeorgian@gmail.com
Combined hereditary thrombophilia is an uncommon entity associated with higher risk of early onset thrombosis. We report a
case of 39-year-old male with combined deficiency of natural anticoagulants (protein C, S and anti thrombin) along with hyper
homocystenemia and factor V Leiden mutation, presenting with life threatening bilateral pulmonary embolism. The clinical
implications of combined thrombophilia are also discussed.
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